Critical care, neurology and analgesia

E Jacqz-Aigrain, I Choonara - Paediatric Clinical Pharmacology, 2021 - taylorfrancis.com
… A PPHN animal model has been developed in fetal lambs by … The impact of midazolam
sorption on pharmacokinetics in … IV Other patients will appear fully conscious and might even be …

Cheyne–Stokes respiration in two sheep during recovery from general anaesthesia for experimental convection enhanced drug delivery

M Cambruzzi, H van Oostrom… - Veterinary Record Case …, 2022 - Wiley Online Library
… vein and the sheep were premedicated with midazolam (Midazolam, … Alterations in the level
of consciousness are associated with … , the pharmacokinetics of alfentanil in sheep has been …

Use and efficacy of analgesic agents in sheep (Ovis aries) used in biomedical research

MW Stillman, AL Whittaker - Journal of the American …, 2019 - ingentaconnect.com
… One group administered the opioids alfentanil and pethidine, … morphine alone did not provide
sufficient analgesia in sheep. … Pharmacokinetics and dynamics of intravenous, intrathecal, …

Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting muscle sympathetic outflow

JC Watso, LN Belval, FA Cimino 3rd… - American Journal …, 2022 - journals.physiology.org
… accelerates hemorrhage-associated hypotension in conscious sheep [intracerebroventricular …
The pharmacodynamics/pharmacokinetics of morphine and morphine metabolites result in …

Opioid Agonists and Antagonists

P Lerche - Pharmacology in Veterinary Anesthesia and …, 2024 - Wiley Online Library
Morphine pharmacokinetics have been determined in calves … have also been reported in
calves, pigs, alpacas, sheep, and … The pharmacokinetics and locomotor activity of alfentanil in …

Choice of sedation in neurointensive care

H Marechal, A Defresne, J Montupil… - Essentials of Evidence …, 2022 - Elsevier
… In the first part of this chapter, we review the pharmacokineticMidazolam is soluble in water
at low pH but its imidazole ring … the free fraction of alfentanil crossing the blood–brain barrier …

Pharmacology related to paediatric anaesthesia

M Maheshwari, S Sanwatsarkar… - Indian Journal of …, 2019 - journals.lww.com
… In a sheep model, cardiac output is found to be inversely … Interaction between propofol and
alfentanil on laryngoscopy … Midazolam offers a better pharmacokinetic profile than diazepam …

[HTML][HTML] Integrative Cardiovascular Physiology and Pathophysiology: Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting …

JC Watso, LN Belval, FA Cimino 3rd… - American Journal of …, 2022 - ncbi.nlm.nih.gov
… accelerates hemorrhage-associated hypotension in conscious sheep [intracerebroventricular …
The pharmacodynamics/pharmacokinetics of morphine and morphine metabolites result in …

Analgesia during parturition in domestic animals: Perspectives and controversies on its use

D Mota-Rojas, A Velarde, M Marcet-Rius, A Orihuela… - Animals, 2022 - mdpi.com
… [4], evaluated the cumulative effect of alfentanil, meperidine, and remifentanil on strips …
pharmacokinetics of the drugs. One example of this was observed in a study of 16 gestating ewes

The minimal anaesthesia model: development and refinement of the concept and subsequent practical applications: a collection of papers and a monograph …

C Johnson - 2020 - mro-ns.massey.ac.nz
… Potent analgesics such as alfentanil (3) appeared to reduce … consideration of cattle only to
include sheep and goats (24). … Intra-articular morphine and saline injections induce release …